Thallium Concentration Urine

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Thallium concentration in urine gives information about a person’s recent exposure to thallium. Higher concentrations generally indicate more exposure. The percentiles (50, 75, 90 and 95) refer to the proportion of the sample that had a urine concentration below a certain level.

Thallium, Urine | ARUP Laboratories Test Directory

Urinary thallium levels may reflect recent or chronic exposure and the presence of thallium in urine after acute exposure may persist for up to several weeks. Concentrations less than 5 µg/L are unlikely to cause adverse health effects while concentrations greater than 500 µg/L have been associated with clinical poisoning.

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Context: Heavy metals, including thallium and lead, are introduced to illicit drug users' body as a result of using drugs such as cocaine and heroin. Objective: This study aimed to determine urine, blood, and hair thallium (Tl) concentrations in illicit opioid users along with the relevant clinical signs and symptoms consistent with thallotoxicosis and to compare them with the corresponding ...

Thallium, 24 Hour Urine | MLabs

Minimum Volume. 1 mL aliquot of 24 hour urine collection. Additional Information. Thallium is a by-product of lead smelting and is found in some depilatories and rodenticides. Thallium is rapidly absorbed via ingestion, inhalation, skin contact, and through mucous

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Cardiac, renal, and hepatic function should be monitored, as should calcium levels. Urine thallium levels above 5 µg/L are abnormal, with levels above 200 µg/L being indicative of poisoning. Thallium blood concentration levels are normal below 2 µg/L, and toxic at concentrations greater than 200 µg/L.

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Only elevated thallium levels in hair, nails, blood, urine, feces and saliva can make a definitive clinical diagnosis. A 24-hour urine thallium concentration, assayed by atomic absorption photospectrometry, is the standard method. Although a urine spot test is faster, it has a high false-positive rate.

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Through this case, we learned that the gradual reduction in blood and urine thallium concentration and the patient's improved condition is correlated with PB and PE treatment. For patients with severe thallium poisoning, this treatment method might be effective; but the exact curative effect is unco

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The same investigators found the thallium concentration in early morning urine samples in nine subjects to range from 0.13 to 1.69 μg/L. Johnson (1976), in a study in New Zealand of 11 subjects with no known exposure to toxic metals, found a mean thallium concentration in the liver of 0.47 mg/kg dry tissue weight, with a range of 0.4-0.9 mg/kg.

Thallium Poisoning · California Poison Control System (CPCS)

Measurable urine concentrations of thallium tend to persist for several days after exposure, and may be used to monitor treatment. A 24-hour urine thallium concentration is the most accurate way to assess thallium toxicity; however, a “spot” urine level provides more rapid confirmation.

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The lowest dissolved thallium concentration for which toxic effects have been reported is 0.15 μmol L −1 for juvenile Atlantic salmon (Zitko et al. 1975). Lethal thallium concentrations for 50 % mortality ranging from 20.9 to 294 μmol L −1 were reported for fish species such as roach, perch and rainbow trout (Pickard et al. 2001).

Thallium in Urine (Creatinine-Corrected), Comparing by Age ...

Thallium concentration in urine gives information about a person’s recent exposure to thallium. Higher concentrations generally indicate more exposure. The percentiles (50 and 95) refer to the proportion of the sample that had a urine concentration below a certain level.

Thallium Toxicity - StatPearls - NCBI Bookshelf

Jul 18, 2021 · Only elevated thallium levels in hair, nails, blood, urine, feces and saliva can make a definitive clinical diagnosis. A 24-hour urine thallium concentration, assayed by atomic absorption photospectrometry, is the standard method. Although a urine spot test is faster, it

Thallium/Creatinine Ratio, Random, Urine - Mayo Clinic ...

Patients exposed to high doses of thallium (>1 g) present with alopecia, peripheral neuropathy and seizures, and renal failure. Normal daily output is less than 1 mcg/day. Exposed patients can have urine output greater than 10 mcg/day.

(PDF) Thallium extraction in urine and water samples by ...

Thallium is readily absorbed by inhalation, ingestion and skin contact. The symptomatology of thallium toxicity was seen in patients with hemorrhage, (PDF) Thallium extraction in urine and water samples by nanomagnetic 4-Aminothieno[2,3-d] pyrimidine-2-thiol functionalized on graphene oxide | Masoud khaleghi Abbasabadi - Academia.edu

Thallium/Creatinine Ratio, Random, Urine - Kootenai Health

Supplies: Urine Tubes, 10 mL (T068) Collection Container/Tube: Clean, plastic urine collection container with no metal cap or glued insert. Submission Container/Tube: Plastic, 10-mL urine tube (T068) or a clean, plastic aliquot container with no metal cap or glued insert. Specimen Volume: 2 mL. Collection Instructions: 1. Collect a random urine ...

A Comparison of Two Methods for the Determination of ...

1·70 fJ.mol/1 (RSD 5·9%, n - 8). Different urine samples with a thallium concentration of 2·00 fJ.mol/1 showed a mean value of 1·95 l.Lmol/1 (RSD 6·2%, n = 12). Interference by normal urine components and protein was not observed. COMPARISON OF DPASV AND AAS In order to compare the two methods, 89 different urine samples, supplemented with ...

Thallium Toxicity Workup: Laboratory Studies, Imaging ...

Jan 11, 2021 · A 24-hour urine thallium concentration is the standard toxicologic method and is assayed by atomic absorption photospectrometry. The normal level is less than 5 mcg/L. A urine spot test can deliver faster results. However, it often gives false-positive results, and it requires the use of 20% nitric acid, which can be dangerous and is usually ...

Thallium poisoning | DermNet NZ

Follow-up – measure thallium concentrations in the blood and urine 3 times per week to confirm a decreasing trend. Prussian blue treatment should be continued until the 24-hour urine thallium concentration returns to the reference range (0-5 mcg/d). Early diagnosis and treatment of thallium poisoning is the key to a favourable recovery.

(PDF) Thallium Toxicity in Humans - ResearchGate

Treatment with chelating agents was ineffective, while HP and treatment with PB drastically decreased the thallium concentration in the urine and blood. With early diagnosis and intervention, four ...

Clinical characteristics and treatment of thallium ...

The median blood thallium concentration of all patients treated with blood purification treatment was 696 (IQR, 293.5–1098.3) ng/ml. Among the early admission patients, seven were given a blood purification treatment based on PB and symptomatic supportive therapy, and the blood thallium concentration of these patients at admission was 1009 ...

Thallium/Creatinine Ratio, Random, Urine - Logan Health ...

Thallium is found in some depilatories and rodenticides. Accidental ingestion may lead to vomiting, diarrhea, and leg pains followed by a severe and sometimes fatal sensorimotor polyneuropathy. Alopecia (hair loss) may occur 3 weeks after poisoning.

Thallium Toxicity Treatment & Management: Prehospital Care ...

Jan 11, 2021 · Admit all patients with significant signs and symptoms of thallium toxicity. Initially measure thallium concentrations in the urine 3 times per week to confirm a decreasing trend. Prussian blue treatment should be continued until the 24-hour urine thallium concentration returns to the reference range (0-5 mcg/d).

Association between maternal thallium exposure and risk of ...

May 01, 2021 · Using the urine sample concentration as the internal exposure biomarker can better reflect the body load than blood sample concentration (Nordberg G. F. et al., 2014). Moreover, we excluded pregnant women with a history of diabetes, so as to avoid possible diabetes-related renal function changes affecting the excretion of urine thallium.

Acute Thallium Poisoning: Series of Ten Cases | SpringerLink

Jul 07, 2011 · Blood and urine samples of eight surviving cases were sent for thallium levels 2 weeks after initiating therapy; the median blood thallium concentration was 10.5 μg/L (range, 5–46 μg/L). The median urine thallium concentration was 79 μg/L (range, 27–150 μg/L).

TOXICOLOGICAL PROFILE FOR THALLIUM

Sep 05, 1989 · The presence of thallium in the urine and hair can indicate exposure to thallium. Tests of your urine can detect thallium up to 2 months. The normal amount of thallium in human urine amounts to less than 1 ppm and 5-10 ppb in human hair. Although thallium can

Thallium, Urine | Test Detail | Quest Diagnostics

Thallium, Urine - Exposure to thallium is primarily through foods and may occur in highly selected industrial environments. Urinary thallium may be used in assessing toxicity. Home . Thallium, Urine. Email. Thallium, Urine. Test Code. 8835. CPT Code(s) 83018, 82570.

Thallium/Creatinine Ratio, Random, Urine - Billings Clinic

Patients exposed to high doses of thallium (>1 g) present with alopecia, peripheral neuropathy and seizures, and renal failure. Normal daily output is less than 1 mcg/day. Exposed patients can have urine output greater than 10 mcg/day. The long-term consequences of such an exposure are poor.

Short-term Thallium Intoxication: Dermatological Findings ...

The Prussian blue treatment was continued for 3 months until the thallium concentration returned to normal ranges. In addition, prolonged hemoperfusion (10 hours) was performed twice 2 months after thallium intoxication in patient 1 and 48 days after thallium intoxication in patient 2 because of a high urine thallium concentration.

Thallium in the Environment and Health Effects | SpringerLink

With regard to population exposure, an epidemiological study in an area with high thallium concentrations in soil and garden vegetables centred on a cement plant, has found evidence of a dose response relationship between thallium concentration in

Thallium (PIM 525) - INCHEM2

Increased excretion of thallium in urine did occur and the concentration of thallium in the blood also increased when dithiocarb was given. However, short-term and long-term therapy with dithiocarb caused loss of consciousness for several hours and electro-encephalogram disturbances persisting for

Acute Thallium Poisoning: Series of Ten Cases | SpringerLink

Jul 07, 2011 · Blood and urine samples of eight surviving cases were sent for thallium levels 2 weeks after initiating therapy; the median blood thallium concentration was 10.5 μg/L (range, 5–46 μg/L). The median urine thallium concentration was 79 μg/L (range, 27–150 μg/L).

Neurotoxicity of thallium: Old issues and new developments ...

May 05, 2021 · The concentration of thallium in maternal urine was quantified using inductively coupled plasma mass spectrometry (ICP-MS). Cord blood leukocyte mtDNAcn was measured by real-time quantitative ...

Thallium toxicity and cruciferous vegetable consumption ...

Dec 12, 2019 · The most accurate way to evaluate thallium burden on the body is via a 24-hour urine collection. Levels above 5 mcg/L are considered abnormal. Levels above 5

Thallium: What Are the Symptoms of Poisoning?

Thallium is a soft, malleable gray metal that was previously widely used in rat poisons and insecticides. Thallium itself and compounds containing the element are highly toxic. It is particularly dangerous because compounds containing thallium are colorless, odorless, and tasteless.

Ambient Water Quality Criteria For Thallium

In the second study (Goenechea and Sellier, 1967) no such distinc- tion is made, and the average urinary concentration of thallium is somewhat lower though similar (Table 2). From the data in the last three papers it seems safe to assume that the concentration of thallium in urine seldom exceeds 1.5 ug/1.

Antimony, Lead, Cadmium, Platinum, Mercury, Tellurium ...

Initial investigations of urine samples from the general population indicate that a reference value for the thallium concentration could be in the order of 100 ng per litre urine . For further details regarding thallium the reader is referred to the general toxicological section of the “Thallium in Urine” method in Volume 5 of “Analyses ...

Impact of urine concentration adjustment method on ...

Urine concentration adjustment approaches compared included urine creatinine, urine osmolality and no adjustment. Median age, blood lead and urine cadmium, thallium and uranium were 13.9 years, 4.0μg/dL, 0.22, 0.27 and 0.04g/g creatinine, respectively, in 512 adolescents.

Toxic Exposure Test | Comprehensive Urine Element Profile

Comprehensive Urine Element Profile. The Comprehensive Urine Element Profile (CUEP) is a toxic exposure panel that measures urinary excretion of 20 toxic metals and 15 nutrient elements. This test is ideal for patients suspected of toxic metal exposure as well as mineral imbalances.